ANGIOPLASTY: DRUG ELUTING STENTS OR DRUG COATED BALLOONS (DCB)

As discussed in an earlier Blog that an Angioplasty is a minimally invasive procedure that can improve blood flow by widening or unblocking a heart-related artery.

A little, specially-made metal tube called a Stent is what a doctor uses to keep a blocked route open. Depending on where it is inserted, the stent resumes blood flow or other fluids. Metal mesh, Cloth, Silicone, or a combination of materials can all be used to make Stents. Metal mesh is utilised to make the stents used in coronary arteries. Larger arteries like the aorta are treated with fabric stents, sometimes known as stent grafts. Silicone is a common material for the stenting utilised in the lungs’ airways.

To prevent a blocked artery from closing, stenting devices can also be coated with medications. There are predominantly two distinct types of stents, such as:

Bare Metal Stents (BMS): These were employed at first, made out of stainless steel was used to make the first stents that were approved for use in heart arteries. Cobalt-chromium alloy has been used to make “second generation” bare-metal stents more recently.

Drug-Eluting Stents (DES): Because bare-metal stents have a higher risk of restenosis, or the development of tissue into the stent that causes artery narrowing, drug-eluting stents (DES) are frequently chosen over them. After the DES is inserted into the coronary artery, it gradually delivers medications to stop the arteries from developing restenosis.

Are there any Side-Effects of Stents?

Stents were first maintained on hand to cure dissections and prevent blood arteries from suddenly closing. Stent implantation entails certain dangers, including:

In-stent Re-stenosis (Re-narrowing of artery or Recurrence of block inside the stent)
Stent Thrombosis (Clotting inside the stent)
Stent Deformation and fracture
Infection & Kidney Damage
Bleeding due to artery damage at the treatment site leading to re-narrowing by clotting of blood.
Allergic reactions
Blood Vessel Damage &
Stroke

The stented arterial segment no longer experiences physiological vasomotion as usual, and the artery may potentially undergo detrimental remodelling. In these situations, despite the possibility of drug-induced bleeding, aspirin and other antiplatelet/anticoagulant medications are administered for several months after the procedure.

Revolutionary Coronary Angioplasty: Drug-Coated Balloon (DCB)

Recently, Drug Coated Balloons (DCB) using Sirolimus drug is safe and effective treatment option, emerged for coronary artery disease. Drug-Coated Balloon (DCB) is a cutting-edge, metal-free therapy that involves coating a balloon with an anti-proliferative medication like Sirolimus to treat vascular diseases and promote healing.

When the balloon is inflated, the medication enters the various layers of the blood artery, promotes healing, and eliminates potential blockages. Using Nanolute technology, the medication is coated onto the balloon to improve drug adhesion to the surface and to effectively deliver the drug to the deepest layer of the vessel. The vessel’s typical physiology is maintained and may even result in late luminal gain (increased diameter of the artery vessel).

No more stent thrombosis (clotting inside the stent), stent deformation and breakage, or prolonged blood-thinner medication needed.
DCB benefits high bleeding risk patients who require surgical treatment after angioplasty.
DCB avoids permanent implantation, promoting quicker recovery of the vessel wall.
It doesn’t leave any residual foreign material inside your artery.
Drug-coated balloons either don’t require blood-thinning drugs or require for a shorter time than other stents.
This ground-breaking technology has revolutionized vascular treatment with exceptional safety.

In India, known as the “Diabetic Capital of the World,” many people suffer from diabetic diffuse coronary artery disease and have smaller-calibre blood arteries. In these circumstances, DCB is a safe alternative.. For Indian individuals with diabetes and coronary artery disease, DCB is very promising. FDA is also keenly looking at this technology with the product already receiving IDE in select indications.

Conclusion

Around the world, there are several active clinical trials with DCB to ascertain its long-term efficacy, in comparison to other stents, and usefulness in diverse clinical scenarios. Because inserting long and small-diameter stents carry a higher risk of clotting and blocking recurrence inside the stent, drug-coated balloons are a blessing for patients. When used properly, drug-eluting stents (DES) and drug-coated balloons are complementary. Hence, DCB has expanded the potential for coronary interventions.

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Terms and Conditions

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Privacy policy

We do not collect any personally identifiable information about you unless you provide it to us voluntarily. If you do not want your personally identifiable information to be collected, please do not submit it to us.

If you do provide us with personally identifiable information, such as your name, postal address, e-mail address, telephone number and other personal information, we may contact you, via e-mail or regular mail to provide you with information we believe may be of interest to you. At the time, you will be offered the opportunity to opt out of this service. We do not sell or transfer to others outside our company the information you send to us, except that your data may be transferred to an outside fulfilment company for processing and mailing purposes only. We consider your e-mail address and any personal information you give to be private and these data will be kept confidential within CMI and by any outside Fulfilment Company. Within CMI, data may be transferred to or accessed by authorized CMI personnel in other countries. At all times, personal data are treated confidentially.

Data that are not personal, such as questions, comments, ideas and suggestions, shall be deemed to be non-confidential, and CMI shall be free to disclose and use the same, without any obligation whatsoever to you, for any purpose and through any means.

In addition, we may store some information on your computer to improve the quality of your visit to our Website. In some cases, this information will help us to tailor the content to your interests, or help us to avoid asking for the same information on repeat visits to the Website. With most Internet browsers, you can erase the information, referred to as “cookies” from your computer’s hard drive, block all cookies or even receive a warning before a cookie is placed on your system. Refer to your browser instructions or help button to learn more about cookies.

We are very concerned about protecting the privacy of children. We do not intend to collect any personally identifiable information from children under 18 years old. If a child has provided us with personally identifiable information, the parent or guardian of that child should contact us.

If at any time you do not wish us to contact you or if you have questions concerning our privacy practices, please feel free to reach out to us.

We are committed to protect the privacy and security of your personal data. We advise you to carefully read this Privacy Notice (“Notice”) so that you are aware of how, where, and why we are using your personal data.

PURPOSE
Your privacy is very important to us. This Notice sets out the way in which we process your information when you use our Website or other digital platforms in accordance with data protection laws.
APPLICABILITY
This Notice applies to individuals visiting our Website. The Notice applies only to the information we collect through our Website, in email, text, forms and other electronic communication received through or in connection with our Website.

INFORMATION WE MAY PROCESS (“Personal Data”)

We may collect personal data on this website, including information we collect while performing business transactions and information we collect from other sources, as permitted by law.

We may collect your personal data including but not limited to

Various usage and user metrics when you visit and use our Website including but not limited to cookies, IP addresses, device and software identifiers, referring and exiting URLs, onsite behaviour and usage information, feature use metrics and statistics, usage history, and location data. While some of this data is captured directly from you, for example, by way of web forms and web log servers, others can be captured indirectly from third parties, for example, tracing organization details, preferences, and interests on the basis of IP address and browsing history respectively.
Information that you provide to us for the purpose of registering to use the Website, subscribing to the Company’s service, posting material, requesting further services and/or applying for a position of employment with us, including but not limited to your job title, name, address, telephone number, e-mail address, social media profile, curriculum vitae / resume, skillset, preferences, and interests.
Information that you provide to us by completing any other forms on the Website or if you contact us with comments or specific requests (including but not limited to your name, address, telephone number, and e-mail address). We may also ask you for information when you report a problem with the Website.
If you contact us, we may keep a record of that correspondence.
We may also ask you to complete surveys that we use for research purposes, although you do not have to respond to them.

MEANS OF PROCESSING DATA

We may process your Personal Data through the following means:

Cookies;
Web job application forms/careers applications;
Web forms;
Newsletter sign-ups;
Registration for an event/activity;
Information request mechanism (for example, Contact Us).

COOKIES

Cookies are alphanumeric identifiers with small amount of data that is commonly used as an anonymous unique identifier. These are sent to your browser from the website that you visit and are stored on your computer’s hard drive. Please note, a cookie in no way gives us access to your computer, that is to say, cookies cannot access any other information on your computer.

Our Website uses these cookies to collect information and to improve our Service by making your interaction with us faster and more secure. They may be used for the purposes of managing your preferences, maintaining and optimizing security, marketing, communication, analytics, and research.

We majorly use below types of cookies:

Essential Cookies or Strictly Necessary Cookies – These cookies are essential to the functioning of our Website and for you to move around the Website. Without these cookies, certain features could not function. No information about your browsing habits is gathered by these cookies.
Functional Cookies – These cookies remember how you prefer to use our Website and improve the way our Website works. These are persistent cookies that help us recognize you as an existing user, so it’s easier for you to return to our Website without signing in again. After signing in, the persistent cookies stay on your browser and will be read when you return on to our sites. These remain on your computer/device for a pre-defined period of time.
Performance Cookies – Some cookies help us with the performance and design of our Website. For example, these cookies show us statistics, which are the most frequently visited pages on the Website, help us record any difficulties you have with the Website, and whether our advertising is effective or not.
Targeting or Tracking Cookies – On certain pages of our Website, we use cookies to help us understand your interests as you browse the Website, so we can tailor and deliver to you a more personalized service in the future. This assists us in delivering relevant, interest-based ads to you.

If you do not want to receive cookies, most browsers allow you to control cookies through their setting preferences. However, if you do turn off cookies in your browser, you will not be able to fully experience some of the features our Website.

GROUNDS FOR LAWFUL PROCESSING OF PERSONAL DATA

When we process your Personal data, we do so primarily in connection with marketing, sale, and promotion of services which we provide or which are procured using our services and to improve and enhance the range of those services and offerings. We may process your personal data for recruitment, communication, sales and marketing, registration and subscriptions purposes, where processing is necessary for the purpose of pursuing our legitimate interests.

USE OF PERSONAL DATA

We generally use the information to establish and enhance our relationship with our users for the following purposes:

Communication – We may use your information to administer and provide services you request or have expressed an interest in, to communicate with you in case of any inquiry or support, for sending newsletters, updates and promotional materials, for seeking your opinion and feedback and personalize, to notify you about changes to our service, and/or tailor any communications that we may send you.
Career Offering – We provide career options on our Website for the users. They can apply to them using our online forms/links by registering with us. Once you are registered with us, we may use your personal data for various job openings that we have in our company and for sending you communication in case of job vacancies.
Advertising – We may use your information to carry out advertising and market research based on behavioural metrics, geo-location data, demographic data and marketing preferences we capture. We may permit certain third party companies to help us tailor advertising based on use.
Activity Tracking – We may use your information to track your activity on our digital platforms and personalize and improve your experience. This can be used to create an individual profile for you so that we can understand and respect your preferences or for profiling purposes to enable us to personalize and/or tailor any marketing communications that you may consent to receive from us.
Optimization- We may use your information to operate, improve and maintain our site, to prevent fraud and abuse.
Information Sharing – We may use and share your information with third parties with whom we have contractual relationship.

We keep your personal data only for the duration of legitimate business requirements or as required by law.

TRANSFERRING YOUR PERSONAL DATA

As a global business, we may transfer your personal data to servers, entities and partners or other trusted third parties based in other countries so that they may process personal data on our behalf. By using our Website or otherwise providing us with your personal data, you agree to us doing so in accordance with the terms of this Privacy Notice and applicable data protection laws and regulations. We will take all steps reasonably necessary to ensure that your data is treated securely and in accordance our data protection policy, which is in line with applicable data protection legislation. We may also transfer your data to third party service providers and web analytics tool providers. CMI may permit certain third party companies to help CMI tailor the advertising that it thinks may be of interest to you, based on your use of our Website.

CHILDREN’S PRIVACY

We understand the importance of taking extra precautions to protect the privacy and safety of children using our Website. The Services are not intended for users under the age of 16. We do not knowingly collect any Personal data from children under 16 or market to or solicit information from anyone under the age of 16. If we become aware that a person submitting Personal data is under 16, we will delete all the information as soon as possible unless it is with the consent and involvement of a parent or guardian. If you believe we might have any information from or about a child under 16, please contact us at privacy@conceptmedicals.com.

SECURITY: HOW SECURE IS YOUR INFORMATION WITH US?

We have implemented appropriate physical, electronic, procedural and managerial procedures to safeguard your information against loss, unauthorized access, misuse or modification. We require any third parties processing your information to do the implement the same levels of protection with respect to your data. We strive to use commercially acceptable means for protecting your information.

CHANGES TO THE NOTICE

This Notice is effective as of {date}*. We reserve the right to update or change this Notice at any time, and we will provide you with the updated Notice when we make any substantial updates at the earliest either through email or by providing a prominent notice of change on the Website. You should check the Notice periodically. Your continued use of the Website after we post any modifications to the Notice on this page will constitute your acknowledgment of the modifications and your consent to abide and be bound by the modified Notice.

THIRD PARTY WEBSITES

From time to time we may provide links to the websites of other organisations, these links are provided for your information only. We have no control over the contents of those sites or resources, and accept no responsibility for them or for any loss or damage that may arise from your use of them.

Your rights and your personal data

We will respect your legal rights in relation to your data. Below are the rights granted to individuals located in the General Data Protection Regulation, and CMI is committed towards protection of the same.

The right to access information: At any point you can contact us to request the information we hold on you as well as why we have that information, who has access to the information and where we obtained the information from. Once we have received your request we will respond within one month.
There are no fees or charges for the first request but additional requests for the same data may be subject to an administrative fee.
The right to correct and update the information: If the data we hold on you is out of date, incomplete or incorrect, you can inform us and your data will be updated.
The right to have your information erased: If you feel that we should no longer be using your data or that we are illegally using your data, you can request that we erase the data we hold.
When we receive your request we will confirm whether the data has been deleted or the reason why it cannot be deleted (for example because we need it for our legitimate interests or regulatory purpose(s).
The right to object to processing: You have the right to request that we stop processing your data. Upon receiving the request, we will contact you and let you know if we are able to comply or if we have legitimate grounds to continue to process your data. Even after you exercise your right to object, we may continue to hold your data to comply with your other rights or to bring or defend legal claims.
The right to data portability: You have the right to request that we transfer some of your data to another controller. We will comply with your request, where it is feasible to do so, within one month of receiving your request.
The right to withdraw your consent: to the processing at any time for any processing of data to which consent was sought. You can withdraw your consent easily by telephone, email, or by post (See Contact Page).
The right to object to the processing: of personal data where applicable.
The right to lodge a complaint: with the Data Protection officer at privacy@conceptmedical.com
How long do we keep your personal data?

We retain personal information for as long as we reasonably require it for legal or business purposes. In determining data retention periods, CMI takes into consideration local laws, contractual obligations, and the expectations and requirements of our customers. When we no longer need personal information, we securely delete or destroy it.